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Novo Nordisk sues Hims over Wegovy copycat drugs

Novo Nordisk has filed a lawsuit against online telehealth provider Hims & Hers, accusing the company of illegally marketing unapproved and cheaper copies of its Wegovy obesity treatments in the United States. The legal action highlights growing tensions in the fast-expanding weight loss drug market, where branded pharmaceutical companies are clashing with telehealth platforms and compounding providers.

Allegations and legal action

The Danish drugmaker is asking a U.S. court to permanently ban Hims from selling compounded versions of its drugs that allegedly infringe on Novo Nordisk’s patents. The company is also seeking damages, arguing that mass-produced compounded drugs violate patent protections and regulatory standards.

Novo Nordisk’s legal counsel stated that the compounded products are untested and pose potential risks to patients, as their safety, efficacy, and quality are not verified by U.S. regulators. According to the company, the justification for compounding no longer applies now that Wegovy and related products are no longer in shortage.

Hims’ response and market impact

Hims & Hers rejected the lawsuit, calling it an attempt by a major pharmaceutical company to limit consumer choice. The telehealth firm said it provides personalized healthcare and that compounded medications play a crucial role in access and affordability for many patients.

The dispute has had an immediate market impact. Novo Nordisk’s shares rose more than 3% following the announcement, while Hims’ stock fell sharply. Over the weekend, Hims said it would stop offering its copycat obesity pill after facing increased scrutiny from regulators and legal pressure.

Regulatory scrutiny and FDA involvement

The lawsuit comes amid growing attention from U.S. regulators. The Food and Drug Administration recently announced plans to take legal action against Hims related to its compounded obesity pill, including restricting access to key ingredients and referring the matter to the Department of Justice.

Compounded drugs are typically allowed on a case-by-case basis when medically necessary, such as when patients cannot tolerate approved formulations. Novo Nordisk argues that producing large quantities of dosage variations does not meet that standard and constitutes unlawful mass compounding.

Broader competition in the obesity drug market

The case reflects intensifying competition in the obesity and diabetes treatment space. As demand for GLP-1 drugs continues to surge, pharmaceutical companies are working to protect market share against both branded rivals and compounded alternatives. Novo Nordisk estimates that more than one million Americans are currently using compounded GLP-1 drugs, even as branded supplies stabilize.

Conclusion

Novo Nordisk’s lawsuit against Hims & Hers underscores the legal and regulatory battles emerging around obesity treatments. As shortages ease and demand remains high, the outcome of this case could shape how compounded drugs are regulated and how telehealth platforms operate within the pharmaceutical marketplace.

Air Canada halts Cuba flights amid fuel shortage

Air Canada has suspended its flights to Cuba following a severe shortage of aviation fuel on the island, highlighting the growing impact of Cuba’s broader energy crisis on international travel. The suspension affects multiple routes from Canada and comes as fuel supplies linked to Venezuela have been disrupted, worsening economic and infrastructure challenges in Cuba.

Suspension of Air Canada services

The suspension took effect on Monday, with Air Canada confirming that it will first focus on repatriating approximately 3,000 passengers currently in Cuba. According to the airline, aviation fuel will not be commercially available at Cuban airports starting Tuesday and is unlikely to resume before at least March 11, based on a Notice to Aviation (NOTAM).

Air Canada typically operates around 16 weekly flights to four Cuban destinations from Toronto and Montreal. All of these services will remain on hold during the fuel shortage. The airline stated it will continue to monitor the situation before deciding when to restart operations.

Fuel dependency and geopolitical pressures

Cuba relies heavily on Venezuela for its jet fuel supply. However, deliveries have been limited since mid-December, after the United States blocked Venezuelan exports. The confiscation of sanctioned Venezuelan oil tankers by the Trump administration has further intensified Cuba’s fuel shortages, contributing to rolling blackouts and widespread disruptions.

President Donald Trump has also warned of potential tariffs against countries that supply oil to Cuba, stating that such measures could target any nation that directly or indirectly provides fuel to the island. These actions have added pressure to Cuba’s already fragile energy system.

Other airlines and official response

Other Canadian carriers, including WestJet and Air Transat, have not yet suspended flights to Cuba. Their continued operations suggest that the situation remains fluid and could evolve depending on fuel availability and political developments.

Cuba’s Foreign Minister, Bruno Rodríguez Parrilla, recently stated that the country has the sovereign right to import fuel from any willing exporter without external interference, criticizing unilateral U.S. measures affecting energy supplies.

Conclusion

Air Canada’s decision to suspend flights underscores how Cuba’s fuel and electricity crisis is spilling into international air travel. While temporary in nature, the disruption reflects deeper geopolitical and economic challenges that could continue to affect tourism, transportation, and daily life on the island in the months ahead.

Measles exposure feared at National March for Life in D.C.

Health officials trace confirmed cases to major January events

Health authorities in Washington, D.C. are warning that confirmed cases of measles may have spread during this year’s National March for Life rally and associated concert, which drew thousands of participants to the nation’s capital in late January.

The DC Department of Health said it was notified of multiple confirmed measles cases involving individuals who were contagious while visiting several locations across the District. Officials are now working to identify and notify people who may have been exposed.

Potential exposure across transit hubs and public venues

According to DC Health, possible exposure sites between January 21 and February 2 include major transportation hubs such as Ronald Reagan Washington National Airport, Union Station, an Amtrak Northeast Regional train, and multiple stations within the Washington Metro system.

Infected individuals also reportedly visited the Basilica of the National Shrine of the Immaculate Conception and Catholic University. Children’s National Hospital issued a public notice after a confirmed measles case from Virginia visited its emergency department while contagious on February 2.

Largest U.S. measles outbreak in decades

The warnings come amid the largest measles outbreak in the United States in decades. The Centers for Disease Control and Prevention reported 733 confirmed cases across 20 states so far this year. According to the agency, 95% of cases involve people who are unvaccinated or whose vaccination status is unknown.

South Carolina remains a major hotspot. Since October 2025, the state has reported 920 confirmed cases, with the outbreak centered in Spartanburg. Health officials there continue to warn of potential exposures in public locations, including retail stores and government offices.

Vaccination urged as global scrutiny grows

Federal health officials are urging Americans to ensure they are vaccinated against measles. Speaking on CNN’s State of the Union, Centers for Medicare & Medicaid Services Administrator Mehmet Oz emphasized that measles immunization guidance has not changed, despite recent rollbacks in recommendations for other vaccines.

International health authorities are also monitoring the situation closely. The World Health Organization’s Pan American Health Organization has invited the United States to an April review of its measles elimination status, warning the country could lose its designation as having eradicated the disease.

DC Health advises anyone who may have been exposed and is not fully vaccinated, or who has a weakened immune system, to contact their health care provider or the health department immediately.

YouTube Music rolls out Premium paywall for lyrics

Lyrics now locked behind paid subscriptions

YouTube Music has begun a wide rollout of a Premium paywall for song lyrics, following several months of testing. Users now need either a YouTube Premium or YouTube Music Premium subscription to view full lyrics within the app.

When the change is active on an account, the lyrics tab in the Now Playing screen displays a notice stating how many free views remain, along with a prompt to “Unlock lyrics with Premium.” Once the free limit is reached, only the first few lines of lyrics are visible, while the rest are blurred and cannot be scrolled.

Five free lyric views before lockout

Under the new system, users are allowed up to five free lyric views before the paywall takes effect. After that point, full lyrics become inaccessible without a paid subscription, marking a significant shift from YouTube Music’s previous approach, where lyrics were freely available.

The rollout appears to be global, suggesting that Google is moving ahead decisively with monetizing a feature that many users consider essential.

Pricing and subscription options

In the United States, YouTube Music Premium costs $10.99 per month and includes ad-free listening, background playback, offline downloads, and AI-powered features such as Ask Music. The broader YouTube Premium subscription costs $13.99 per month and extends those benefits to the main YouTube app.

Part of a broader monetization push

The lyrics paywall aligns with Google’s broader strategy to grow subscription revenue. Earlier this week, the company reported more than 325 million paid subscriptions across its consumer services, driven largely by strong adoption of Google One and YouTube Premium.

In 2025, YouTube generated more than $60 billion in revenue from advertising and subscriptions combined, highlighting the platform’s increasing reliance on paid features to sustain growth.

Eli Lilly to acquire Orna Therapeutics in $2.4B deal

In vivo CAR-T and circular RNA at the core of the agreement

Eli Lilly and Company has announced a definitive agreement to acquire Orna Therapeutics, a biotechnology company focused on engineering immune cells directly inside the human body. The transaction could be worth up to $2.4 billion in cash, including an upfront payment and additional milestone-based payments tied to clinical development progress.

The acquisition reflects Lilly’s strategic push into next-generation genetic medicines and cell therapies, particularly for patients with autoimmune diseases who currently have limited treatment options.

Orna’s circular RNA platform explained

Orna Therapeutics is developing a new class of therapeutics based on fully engineered circular RNA combined with proprietary lipid nanoparticle delivery systems. Unlike traditional messenger RNA approaches, circular RNA is designed to produce more durable and sustained protein expression within the body.

This technology enables the body itself to generate therapeutic cell responses, potentially eliminating the need for complex and costly ex vivo cell manufacturing. Preclinical and early experimental data suggest this approach could unlock treatments that are not feasible with current RNA or cell therapy platforms.

Focus on autoimmune diseases with in vivo CAR-T

Orna’s lead program, ORN-252, is a clinical trial-ready CD19-targeting in vivo CAR-T therapy designed to treat B cell-driven autoimmune diseases. Early autologous CAR-T studies have already demonstrated the promise of cell therapy in autoimmune conditions, but widespread adoption has been limited by logistical and financial barriers.

By enabling CAR-T generation directly inside the patient, Orna’s platform aims to dramatically simplify delivery while expanding access to a broader patient population.

Strategic rationale for Lilly

Lilly views the acquisition as an opportunity to potentially establish an entirely new class of genetic medicines. According to company leadership, integrating Orna’s circular RNA and lipid nanoparticle technologies could accelerate the development of scalable, patient-centric therapies across immunology and beyond.

Following the close of the transaction, Lilly will determine the accounting treatment under Generally Accepted Accounting Principles, and the deal will be reflected in its financial results and guidance.

Transaction details and outlook

Paul, Weiss, Rifkind, Wharton & Garrison LLP is serving as legal counsel to Lilly, while Lazard is acting as financial advisor to Orna Therapeutics. Goodwin Procter LLP is providing legal counsel to Orna.

While the companies expressed optimism about the potential of the combined technologies, the transaction remains subject to the inherent risks of drug research, development, and commercialization, with no guarantee of future commercial success.

Brain training game linked to lower dementia risk

Long-term study shows lasting protective effects

A large, long-term study has found that playing a specific type of brain training video game may help protect against dementia for decades. Researchers say the findings provide the strongest evidence so far that targeted cognitive training can create durable changes in the brain and lower the risk of Alzheimer’s disease and other forms of dementia.

The research, published in the journal Alzheimer’s & Dementia: Translational Research & Clinical Interventions, followed participants from the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) trial for up to 20 years. Participants who completed up to 23 hours of a cognitive exercise known as speed training over a three-year period had a 25% lower risk of developing dementia compared with those who received no training.

Details of the ACTIVE trial

The ACTIVE study is a large randomized controlled trial funded by the National Institutes of Health that enrolled nearly 3,000 adults aged 65 and older who had no significant cognitive impairment at the start. Participants were drawn from six geographic regions, with women making up the majority and roughly a quarter of the group representing minority populations.

Study volunteers were assigned to one of three cognitive training programs, speed training, memory training, or reasoning training, or to a control group that received no training. Initial training consisted of up to 10 sessions over five weeks, with about half of participants in each group later receiving booster sessions over three years.

Only those who completed speed training with booster sessions showed a significant reduction in dementia risk. Memory and reasoning training did not demonstrate a protective effect.

Why speed training may work

Speed training focuses on improving how quickly and accurately the brain processes visual information. Participants were asked to rapidly identify objects on a screen and make decisions, a process similar to the visual demands of driving. Researchers believe this type of training relies on implicit learning, which builds unconscious skills and habits and may lead to long-lasting neural changes.

Experts say this form of training may enhance neuroplasticity and cognitive reserve, the brain’s ability to resist damage from aging or disease. Unlike other training types, speed training is adaptive, meaning the difficulty increases as performance improves, which may further strengthen its impact.

Implications for brain health

The speed training used in the study is now available through the BrainHQ platform as an exercise called “Double Decision.” Researchers currently recommend it primarily for adults over 65, though it is possible that starting earlier in life could also provide benefits. More research is needed to determine its effectiveness in younger age groups.

While the findings are encouraging, experts stress that dementia prevention requires a multifaceted approach. Lifestyle factors such as regular exercise, managing blood pressure and blood sugar, addressing hearing and vision loss, staying mentally and socially engaged, and keeping up with vaccinations may all contribute to long-term brain health.

Washington Post Cuts Raise Fears of a “Death Spiral”

The Washington Post’s former executive editor Marty Baron has warned that the newspaper’s future is increasingly uncertain after sweeping layoffs reduced the organization’s scale and ambitions. Baron, who led the Post during a period of major growth and investigative prominence, said the paper’s diminished scope could translate into subscriber losses and a potentially destabilizing cycle of decline.

Baron warns of shrinking ambitions

Under Baron’s leadership, the Washington Post won 11 Pulitzer Prizes and expanded to more than 1,000 journalists. In a recent interview, he said the organization’s “aspirations” have been reduced and expressed concern that fewer resources could lead to fewer subscribers. “I hope it’s not a death spiral, but I worry that it might be,” Baron said.

Large-scale layoffs reshape the newsroom

The warning comes as the Post executed one of the largest rounds of job cuts in modern American newspaper history. Nearly one-third of the company was laid off, from a workforce that had stood at about 2,500 employees in late 2023 before earlier buyouts.

The reductions affected core newsroom functions. The paper shuttered its sports department and sharply reduced local coverage, style, and international reporting teams. Audio and video operations, already weakened by earlier cuts, were also further reduced, alongside cuts to commercial staff.

A narrower editorial focus and tougher competition

Editor in chief Matt Murray told staff that the organization has a plan to “survive and thrive” and said the largest reporting group will be its politics and government team. The Post will continue covering national news, science, technology, climate, and business, though with smaller staffs.

However, a Post that concentrates more heavily on federal politics and the Trump administration faces intense competition from outlets that have built their identity around those beats, including Politico, Axios, and newer niche publications such as Punchbowl News.

Ownership questions and political pressure

Baron said he believes owner Jeff Bezos has changed since purchasing the paper in 2013. He attributed part of that shift to Donald Trump’s return to the White House and the possibility of retaliation against Bezos’s other businesses, including Amazon and Blue Origin. Baron said he understands the fear of political consequences, but argued that the Post’s civic role should remain paramount.

Criticism has also centered on publisher Will Lewis, who was hired in late 2023 to help reverse the newspaper’s financial struggles. Baron questioned Lewis’s visibility during the announcement of layoffs, suggesting leadership should have been more directly present in a moment of major upheaval.

Subscriber concerns and potential fallout

The layoffs follow a period of reputational turbulence. In late 2024, the Post lost hundreds of thousands of subscribers after Bezos shelved a planned endorsement of Kamala Harris for president and shifted the opinion pages toward a narrower focus. Observers now fear the latest cuts could prompt a new wave of cancellations and deepen the paper’s financial strain.

Some longtime insiders and the union representing many employees have called for Bezos to sell the paper, arguing that if ownership is unwilling to invest in the Post’s mission, it should have a different steward. Baron, however, raised an open question about who any buyer would be.

Conclusion

The Washington Post is entering a new phase as a smaller newsroom with a sharper focus on politics and government coverage. While leadership says the plan is to rebuild for the AI era and restore sustainability, critics worry the loss of breadth and staffing could weaken subscriber appeal and reduce the paper’s role as a major national and international news institution.

Morocco Evacuates Over 108,000 as Flood Risk Intensifies

Moroccan authorities ordered large-scale evacuations on Wednesday across flood-prone areas in the country’s northwest as heavy rainfall, overflowing rivers and emergency water releases from dams sharply increased the risk of flooding.

According to the Interior Ministry, 108,432 people have been evacuated so far. Helicopters have been deployed for rescue operations, and the army has been on the ground since Friday following a red alert for continued heavy rainfall.

Northwest regions under severe pressure

The evacuations primarily affect the Gharb region, a low-lying agricultural area that plays a critical role in Morocco’s wheat production. Weeks of intense rain, combined with poor drainage and flat terrain, have left large parts of the region vulnerable to inundation.

Official data shows rainfall levels are 215% higher than last year and 54% above the historical average, overwhelming rivers and reservoirs across the northwest.

Larache province hit hardest

Evacuation orders were issued in several areas of Larache province, including Ksar El Kebir, Souaken, Ouled Ouchih, the Larache industrial zone and communities near the Loukous River.

Authorities said approximately 85% of Ksar El Kebir’s population has already left the city. State television showed evacuees receiving shelter, food and basic services in temporary camps.

Large sections of Ksar El Kebir remain submerged after the Loukous River burst its banks last week. Residents reported electricity cuts in several neighborhoods.

Dam capacity raises further concerns

Officials are closely monitoring the Oued Makhazine dam near Ksar El Kebir, which is operating at 146% of capacity after weeks of sustained rainfall. The water ministry warned that additional water releases downstream may be necessary to reduce pressure on the structure.

Nationwide, Morocco’s dam-filling rate has risen sharply to nearly 62%, compared with 27% a year ago. Several major dams are being partially emptied to absorb further inflows.

Calls for disaster designation

Rights groups have called on the government to declare the affected areas disaster-stricken, a move that would allow residents to access insurance coverage for flood-related damage.

The exceptional rainfall has effectively ended a seven-year drought that previously forced Morocco to accelerate investments in desalination infrastructure. While water reserves have recovered rapidly, authorities warn that flood risks remain high as more rain is forecast.

WHO Study Finds Millions of Cancers Are Preventable

A new global study led by the World Health Organization suggests that a large share of cancer cases could be avoided through prevention. According to the analysis, nearly 40 percent of cancers diagnosed worldwide in 2022 were linked to modifiable risk factors, highlighting the potential impact of targeted public health measures.

Key Findings From the Global Study

The research, conducted by the International Agency for Research on Cancer and published in Nature Medicine, examined 36 cancer types across 185 countries. It found that 7.1 million of the 18.7 million new cancer cases recorded in 2022 were associated with modifiable risk factors.

These factors include tobacco and alcohol use, high body mass index, insufficient physical activity, air pollution, ultraviolet radiation, and occupational exposure to toxins such as asbestos. For the first time in a study of this scope, infectious agents such as hepatitis B and human papillomavirus were also included.

Infectious Diseases and Preventable Cancers

The inclusion of infections revealed significant patterns, particularly among women. Cancers caused by infections accounted for 2.7 million preventable cases among women, or nearly 30 percent. Human papillomavirus related cancers, especially cervical cancer, represented the largest share of preventable cancers in women worldwide.

Despite the availability of effective vaccines, preventable HPV related cancers remain prevalent in regions such as Latin America and Sub Saharan Africa. Limited access to vaccination, gaps in screening, and vaccine hesitancy continue to drive higher incidence and mortality rates.

Differences Between Women and Men

The study also highlighted important differences in cancer risk between sexes. Among men, behavioral factors were the dominant contributors to preventable cancers. Smoking alone accounted for a substantial share, with 4.3 million preventable cases, or more than 45 percent of male cancer cases linked to modifiable risks.

Lung cancer, one of the most common cancers globally, showed similar underlying risk factors for both men and women, including tobacco use and air pollution. However, the number of cases was significantly higher among men, underscoring how exposure and behavior patterns influence outcomes.

Regional and Social Inequalities

The burden of preventable cancer varies widely by region. In higher income countries, widespread vaccination and screening have reduced certain cancer rates dramatically. In contrast, lower income regions continue to face higher preventable cancer burdens due to limited healthcare access and socioeconomic barriers.

Experts emphasized that prevention depends not only on individual behavior but also on health systems, education, and policy support.

Looking Ahead

With global cancer cases projected to rise by more than 50 percent by 2045, the researchers stress the urgency of prevention. They argue that targeted interventions tailored to regional, social, and gender specific realities could significantly reduce future cancer incidence.

Conclusion

The WHO backed study reinforces that millions of cancer cases could be avoided through proven prevention strategies. While not all cancers are preventable, addressing modifiable risk factors through vaccination, lifestyle changes, and environmental protections offers a powerful path to reducing the global cancer burden.

Apple Adds Agentic AI Coding Tools to Xcode

Apple has taken a major step forward in AI assisted software development with the release of Xcode 26.3. The update introduces native support for agentic coding tools, allowing developers to use advanced AI agents directly inside Apple’s official development environment to build, test, and modify applications with greater automation and transparency.

Xcode 26.3 and Agentic Coding

The Xcode 26.3 Release Candidate is now available to Apple Developers through the developer website, with a wider rollout via the App Store expected soon. The update enables direct integration with agentic AI tools such as Anthropic’s Claude Agent and OpenAI’s Codex.

This builds on last year’s Xcode 26 release, which first introduced support for conversational AI models like ChatGPT and Claude. The new agentic approach expands those capabilities, allowing AI models to perform multi step actions across a project rather than responding only to isolated prompts.

What the AI Agents Can Do

With agentic coding enabled, AI tools can explore an app project, understand its structure and metadata, write new code, run builds, execute tests, and identify and fix errors. The agents also have access to Apple’s up to date developer documentation, ensuring the use of current APIs and recommended best practices.

Developers can issue instructions using natural language, such as requesting a new feature built with a specific Apple framework and defining how it should look and behave within the app.

Technical Foundation and MCP Support

Xcode 26.3 uses the Model Context Protocol, or MCP, to expose its internal capabilities to AI agents. This allows Xcode to work not only with Apple approved tools but with any external MCP compatible agent.

Through MCP, agents can handle project discovery, file management, previews, snippets, documentation lookup, and code changes, all while remaining tightly integrated into the Xcode workflow.

Developer Controls and Workflow

Developers can select which AI agent and model version they want to use from Xcode’s settings, including options such as GPT 5.2 Codex or smaller model variants. Accounts can be connected either by signing in to supported services or by providing API keys.

As an agent works, it breaks tasks into visible steps, highlights code changes directly in the editor, and records a detailed transcript explaining what it is doing and why. Xcode also creates automatic milestones, allowing developers to revert to earlier versions of their code at any time.

Learning and Transparency Benefits

Apple believes this transparent, step by step approach will be especially valuable for newer developers. To support adoption, the company is hosting a live code along workshop on its developer site, where users can follow along in real time using their own copy of Xcode.

The agents also verify that generated code works as expected by running tests, and they can iterate further to resolve issues. Apple notes that prompting agents to plan before coding can improve results by encouraging structured reasoning.

Conclusion

The introduction of agentic coding in Xcode 26.3 marks a significant evolution in Apple’s developer tools. By combining AI agents with deep IDE integration, Apple is positioning Xcode as a more powerful, flexible, and educational environment, accelerating app development while keeping developers firmly in control.